Chung Hsuan (Winston) Chen got his B.S. degree from Chemistry Department, National Taiwan University in 1969. He got his Ph. D in Chemical Physics from University of Chicago in 1974, then he went to Oak Ridge National Laboratory to become a research staff. In 1989, he became Group Leader of Photophysics. During his tenure at Oak Ridge National Lab, his major effort was placed on development of ultra-sensitive detection technology. They include the first detection of single atom and isotope-selective atom counting. He is also one of the pioneers in developing mass spectrometry for DNA analysis and sequencing. His recent research has focused on novel mass spectrometry technology developments including cell mass spectrometer, accelerator mass spectrometer and portable biomolecular mass spectrometer. In 2007, he was appointed as Director of Genomics Research Center in Academia Sinica. He also has adjunct professor appointment at Chemistry Department, National Taiwan University. He has published more than 230 papers in referred journals. He obtained 3 R&D-100 awards, He was elected as Fellow of American Physical Society in 1993, and AAAS in 2009 due to his contribution on ultrasensitive detection technology development. He was elected as Member of Academia Sinica in 2010.